Aston Villa secured a 2-1 victory at Basel on Thursday, with goals from Evann Guessand and Youri Tielemans keeping their Europa League campaign on a strong footing.
Florian Thauvin headed in Payet's free kick after 15 minutes and Clinton Njie calmly slotted home in the 63rd to put Marseille in the driving seat against the Austrian champions.
IMAGES from the UEFA Champions League matches played on Wednesday
IMAGES from the UEFA Champions League matches played on Tuesday.
IMAGES from the UEFA Champions League matches played on Wednesday.
IMAGES from the Champions League matches played on Wednesday.
Atalanta's Josip Ilicic and Robin Gosens scored quickfire second-half goals to give them a comfortable 2-0 win over a toothless Liverpool
Salzburg won the Austrian Cup with a ruthless 5-0 destruction of second tier Austria Lustenau in the final as the season resumed following the coronavirus stoppage on Friday.
Liverpool stuttered into the quarter-finals of the Champions League with a 2-1 aggregate win over Inter Milan after suffering a 1-0 loss to the Italian side, who were reduced to 10 men, at Anfield on Tuesday.
A round-up of Tuesday's action in the UEFA Champions League.
Images from UEFA Champions League matches played on Wednesday.
A round-up of Wednesday's action in the UEFA Champions League.
A round-up of Wednesday's action in the UEFA Champions League.
Leaders Porto suffered a shock 2-1 defeat at Famalicao as Portugal's Primeira Liga became the latest league to return to action following the coronavirus stoppage on Wednesday.
A round-up of Tuesday's action in the UEFA Champions League.
A round-up of Wednesday's action in the UEFA Champions League.
With the away goals rule no longer in place this season, PSV missed a string of chances to force extra time with Eran Zahavi hitting the crossbar from three metres with the goal at his mercy in the 62nd minute.
Liverpool thrashed Atalanta 5-0, Real Madrid boosted their chances of reaching the Champions League knockout stages with a 3-2 home victory over Inter Milan and Bayern Munich came from behind to crush RB Salzburg 6-2.
While Lyon rallied to hold Leipzig 2-2 after a Memphis Depay strike, it was the English clubs who made a mark on the night. Liverpool and Chelsea moved into the last 16 with contrasting wins and now all four English clubs, including Manchester City and Tottenham Hotspur, are in the Champions League knockouts this season.
IMAGES from the Champions League matches played on Wednesday.
Arsenal beat Liverpool 5-4 on penalties on Saturday to lift the FA Community Shield, the curtain-raiser for the English domestic season, after the two sides played out a 1-1 draw on a chilly afternoon at Wembley.
A summary of Tuesday's Group stage matches in the UEFA Champions League.
A round-up of Wednesday's night's UEFA Chmpions League matches.
Goals in each half from Kai Havertz and Christian Pulisic earned defending champions Chelsea a solid 2-0 first-leg victory over Lille in the Champions League last 16 on Tuesday.
A summary of Wednesday's matches in the UEFA Champions League.
Chelsea's Ruben Loftus-Cheek had a Europa League night to remember by scoring the first hat-trick of his career as the midfielder inspired them to a 3-1 home win over Belarus champions BATE Borisov on Thursday.
IMAGES from the Europa League matches played on Thursday
Rattled by embarrassing domestic defeats, Chelsea looked jittery before Olivier Giroud settled their nerves with a close range tap-in shortly after halftime at StamfordBridge following good work by N'Golo Kante and Willian in the build-up.
Fellow Serie A sides Atalanta and Lazio also won while Portugal's Vitoria Guimaraes began their match against Salzburg with not a single European player in the team.
Borussia Dortmund snatched a late goal at Atalanta to progress with a 1-1 draw, while AC Milan and Atletico Madrid, both with three-goal leads from the away legs, completed the formality of qualifying with 1-0 wins at home on Thursday.
A summary of Wednesday night's action in the UEFA Champions League.
Images from the UEFA Champions League matches played on Wednesday.
Lazio won 2-0 at Legia Warsaw on Thursday to qualify for the Europa League knockout stages after a tie marred by violence when Italian fans fought with Polish police on the way to the stadium.
Luka Modric pulled one back for Zinedine Zidane's shellshocked side with a brilliant strike from distance early in the second half before substitute Vinicius Jr reduced the deficit to one goal.
Atletico Madrid delayed Barcelona's La Liga title celebrations by beating Valencia 3-2 at home in an entertaining game on Wednesday at a sparsely attended Wanda Metropolitano stadium.
It was a dramatic night at the Champions League as Barcelona's Anssumane Fati -- 17 years and 40 days old - became the youngest to net a goal in the competition. Last season's semi-finalists, Ajax were eliminated by Valencia while Napoli's coach Ancelotti was shown the door despite the team's progress. Here are Images from the Champions League matches played on Tuesday
Images from the Champions League matches played across Europe on Tuesday